Sean wrote:
I would like for it to be acrylic as it is much stronger and about
half the weight of glass. I was thinking about building a tank about
8 feet long and about 4 feet deep (front to back) by about 5 feet
high (floor to ceiling). This may be well beyond 300Gs,
[...]
water weight calcs....

Well, that part is simple: for all practical purposes 1 liter of fresh water
has a weight of 1 kg.

So let's do it in ISO units: 8'x4'x5' is about 2.4mx1.2mx1.5m = 4.32 cubic
meter

In other words your are dealing with a tank of about 4.32 tons of
freshwater, total weight probably somewhere near 5 tons. Sal****er even a
bit more. Or converted back 4230 liter are roughly 1100-1200 gallons.

I suggest you contact an architect because unless you are living in a former
factory your floors are certainly not designed to take that kind weight.

Good luck

jue