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IWS Health
The most frequently mentioned health disorders in the IWS breed include the following: hip dysplasia, hypothyroidism, allergies, immune problems, seizures, coat loss, cancer, eyelid disorders (especially entropion), toenail disorders (paronychia), and temperament problems. There are rumors, but no hard proof of, von Willebrand's Disease (where proper blood clotting does not occur) and progressive retinal atrophy. Both of the latter can be tested for, although the value of the current vWD blood test is subject to legitimate criticism. Conservative recommendations for pre-breeding health screens include certification by OFA for hips after the second birthday (elbow problems are far less frequent, but some breeders now do OFA elbow certifications, too); periodic assessment of thyroid function by a "complete thyroid panel" (contact the Animal Health Diagnostic Laboratory in Lansing, Michigan, at (517) 353-0621, for details; not all thyroid tests are equally informative); and periodic certification of normal vision by CERF. Any animal with severe allergies or temperament problems should not be bred. The toenail disorder seen in the IWS is not at all well understood. It seems to appear in young adults who may begin to manifest symptoms by chewing on the feet. The problem can occur in dogs whose feet are regularly trimmed. The toenail's interior "core" becomes mushy and may secondarily become infected with bacteria and fungus, causing a foul odor. The disease will progress even if infection is not present. The outer shell of the nail eventually falls off, exposing the raw "quick". One or many toes may be affected. Some owners report satisfactory treatment by eliminating dietary allergens. Others have opted to have the dog's toes removed. Treatment is necessary to avoid suffering. A genetic component is suspected due to occurrence in related individuals, but very little is known of this condition. Since several of the disorders mentioned above are physiologically interrelated, an explanation is included here. The immune system protects the body from foreign substances, including infectious agents like bacteria and viruses. An underactive immune system thus leaves the body vulnerable to infection. An underactive immune system also contributes greatly to the development of all kinds of cancer. The characteristic cancers and infections that develop with the human disease AIDS (acquired immunodeficiency syndrome) are perfect examples of the dangers of immune suppression. An overactive immune system is equally harmful to health. There are two main forms in which this occurs: autoimmunity and allergies. Autoimmunity occurs when the immune system mistakenly targets one of the body's own normal components. This can lead to serious consequences. The human disease multiple sclerosis is an autoimmune disorder, and there are many others. In dogs, autoimmune thyroiditis is the leading cause of underactive thyroid gland function (= hypothyroidism). It is important to note that the thyroid gland is largely responsible for regulating the rate of protein production in the body. Underactive thyroid means a slower rate of protein production. Because the skin and coat are made up of so much protein, hypothyroidism often results in coat loss or thinning. Likewise, the immune system's proper function depends utterly on the production of proteins (antibodies). Hence, it may happen that autoimmune thyroiditis (overactive immune system) causes hypothyroidism, which then secondarily causes an underactive immune system. The body's physiology is full of cycles like these that must be borne in mind as treatment is designed. Fortunately, hypothyroidism is easy to treat, so that part of the cycle can be broken once proper testing has established a hypothyroid diagnosis. Allergies also represent an overactive immune system, at least initially. The body mounts a vigorous immune response to a relatively harmless foreign substance, like pollen or dust or a diet component. When allergies persist over long periods, the immune system begins to pour more and more effort into the allergic response alone, exhausting its resources to fight off really dangerous infections. Hence, a dog with bad allergies may develop skin infections that it is relatively helpless to fight off. The body's normal reaction to severe stress (pain, anxiety, etc.) includes the release into the bloodstream of an immune-suppressing hormone known as cortisone. Normally, stress is short-lived and the cortisone production is also short-lived. If stress is chronic, however, cortisone release will also be chronic, which can actually collapse the immune system. This is why severely stressed animals (and people!) often fall ill. The fact that cortisone exists in the body, however, means that medical science can use a synthetic analog of cortisone to interrupt severe immune reactions when it is necessary. For example, a sudden allergic reaction to fleas can be greatly reduced by the drug called prednisolone, a cortisone relative that mimics its action. Even with synthetic hormone, however, prolonged use will collapse the immune system, possibly leading to even greater problems. That is why medical practitioners, including vets, are hesitant to keep a patient on long-term cortisone, even though it relieves initial symptoms. The long-term risk to the immune system just cannot be ignored. This presents a dilemma for the dog with chronic allergies. Letting the allergies run wild will eventually exhaust the immune system, making the animal vulnerable to infections and/or cancer. Overtreating the allergies with cortisone will do the same. REMEMBER: "This is worth repeating for benefit of al newbies! Jo Ann asked Dr. Solo to remind people that while she has retired from selling GF (and sold the business to Ken Fischer http://dandyorandas.com/) she has NOT retired from helping people with sick GF and koi FOR FREE. 251-649-4790 phoning is best for diagnosis. but, can try email put "help sick fish" in subject. Get your fish at Dandy Orandas Dandy Orandas Dandy Orandas........you guys got that DANDY ORANDAS |
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